Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

Blog Article

one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor used in the treatment method of a number of myeloma. Its synthesis or review is critical for making certain the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound inside the synthesis of imatinib, a drug that targets specific different types of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their study is crucial for optimizing the manufacturing process and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to deal with breast cancer, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist used in the remedy of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is used in 7-dihydro-4-oxo-1H-pyrrolo[2 the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the therapy of colorectal cancer and modest mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, which have numerous programs, like antiviral Qualities.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for variety two diabetic issues that inhibits the enzyme DPP-four to CAS NO.132127-34-5 control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of various gluconic acid derivatives, which can be Utilized in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication used to deal with style two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).